The herd immunity threshold (HIT) is computed using the formula HIT=1−R01. This represents the immune fraction of the population needed so that each case infects fewer than one other on average, stopping sustained spread.
Conditions: The narration adds assumptions of random mixing and a fully effective vaccine.; The goal stated is that each case infects fewer than one other on average.
The herd immunity threshold (HIT) is computed using the formula HIT=1−R01. This represents the immune fraction of the population needed so that each case infects fewer than one other on average, stopping sustained spread.
Conditions: The narration adds assumptions of random mixing and a fully effective vaccine.; The goal stated is that each case infects fewer than one other on average.
R0 should be used early in an outbreak when the whole population is susceptible and when a growth rate and serial interval are available. Once some immunity builds up in the population, one should switch to using the effective reproduction number instead.
Conditions: Use R0 early in an outbreak with a fully susceptible population.; Use it when a growth rate and serial interval are available.; Switch to effective R once immunity builds.
R0 should be used early in an outbreak when the whole population is susceptible and when a growth rate and serial interval are available. Once some immunity builds up in the population, one should switch to using the effective reproduction number instead.
Conditions: Use R0 early in an outbreak with a fully susceptible population.; Use it when a growth rate and serial interval are available.; Switch to effective R once immunity builds.