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Answers for “如果人群中已存在部分免疫力,应该使用什么指标?”

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The herd immunity threshold (HIT) is computed using the formula HIT=1−1R0\mathrm{HIT} = 1 - \frac{1}{R_0}. This represents the immune fraction of the population needed so that each case infects fewer than one other on average, stopping sustained spread.

Conditions: The narration adds assumptions of random mixing and a fully effective vaccine.; The goal stated is that each case infects fewer than one other on average.

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R0R_0 should be used early in an outbreak when the whole population is susceptible and when a growth rate and serial interval are available. Once some immunity builds up in the population, one should switch to using the effective reproduction number instead.

Conditions: Use R0R_0 early in an outbreak with a fully susceptible population.; Use it when a growth rate and serial interval are available.; Switch to effective RR once immunity builds.